Environmental factors involved in the pathogenesis of IBD include a wide range of habits and behaviors that disrupt the natural bacterial flora of the digestive system, as well as factors that support and cause intestinal inflammation. Among these aspects, an important role is assigned to improving hygiene conditions in society, the use of antibiotics and preventive vaccinations, purifying drinking water and changing eating habits, especially excessive consumption of refined sugar, saturated fats and highly processed foods.
These factors cause delayed exposure to microbial antigens at an early age, which leads to poor stimulation of the immune system and less developed defense mechanisms involved in fighting infection in adulthood. Moreover, the use of antibiotics eliminates not only pathogenic microorganisms, but also those that make up the vegetative intestinal microflora necessary for the proper functioning of the digestive tract. All this leads to a serious imbalance of the intestinal microflora, which significantly contributes to the formation of IBD.
Among the environmental factors involved in the pathogenesis of UC and CD, much attention is paid to cigarette smoke. Many studies show a correlation between the incidence of IBD and smoking addiction. In the case of CD, there was an increase in the incidence of heavy smokers, while in the case of UC, it was proven that smoking reduces the likelihood of developing the disease and relieves symptoms during exacerbation.
In aspects of the pathogenesis of IBD, mental stress is also often mentioned as one of the causes of these diseases, but studies have not yet shown a clear effect of this factor. Admittedly, it has been observed that people suffering from both UC and UC are hypersensitive people, easily susceptible to stressful situations, and relapses of the disease are often associated with psychological trauma, difficult life situations, or severe stress, but it is assumed that stress itself is not the culprit of these diseases.
This can only worsen the symptoms or lead to relapses due to the stimulating effect of stress on the motility of the gastrointestinal tract, causing secretory changes in the intestinal mucosa and increasing its permeability, which leads to activation of mast cells and damage to mucin or negatively affects the regenerative ability of the gastric mucosa.
It should be emphasized that none of the environmental factors alone can cause IBD. It can only be used in case of recurrence of an exacerbation of the disease and maintenance of inflammation. For the development of UC or CD, environmental factors must interact with immunological and genetic stimuli. Real free porn movies https://exporntoons.net online porn USA, UK, AU, Europe.
These factors cause delayed exposure to microbial antigens at an early age, which leads to poor stimulation of the immune system and less developed defense mechanisms involved in fighting infection in adulthood. Moreover, the use of antibiotics eliminates not only pathogenic microorganisms, but also those that make up the vegetative intestinal microflora necessary for the proper functioning of the digestive tract. All this leads to a serious imbalance of the intestinal microflora, which significantly contributes to the formation of IBD.
Among the environmental factors involved in the pathogenesis of UC and CD, much attention is paid to cigarette smoke. Many studies show a correlation between the incidence of IBD and smoking addiction. In the case of CD, there was an increase in the incidence of heavy smokers, while in the case of UC, it was proven that smoking reduces the likelihood of developing the disease and relieves symptoms during exacerbation.
In aspects of the pathogenesis of IBD, mental stress is also often mentioned as one of the causes of these diseases, but studies have not yet shown a clear effect of this factor. Admittedly, it has been observed that people suffering from both UC and UC are hypersensitive people, easily susceptible to stressful situations, and relapses of the disease are often associated with psychological trauma, difficult life situations, or severe stress, but it is assumed that stress itself is not the culprit of these diseases.
This can only worsen the symptoms or lead to relapses due to the stimulating effect of stress on the motility of the gastrointestinal tract, causing secretory changes in the intestinal mucosa and increasing its permeability, which leads to activation of mast cells and damage to mucin or negatively affects the regenerative ability of the gastric mucosa.
It should be emphasized that none of the environmental factors alone can cause IBD. It can only be used in case of recurrence of an exacerbation of the disease and maintenance of inflammation. For the development of UC or CD, environmental factors must interact with immunological and genetic stimuli. Real free porn movies https://exporntoons.net online porn USA, UK, AU, Europe.